Retrospective comparative study on acute-phase clinical characteristics between vascular vertigo/dizziness and vestibular neuritis
LI Lili
HE Lili
LIU Yan
Abstract：Objective To investigate differences in clinical characteristics between patients with vascular vertigo/dizziness(VVD)and vestibular neuritis(VN)during the acute phase,to provide evidence-based support for rapid differ‐ential diagnosis.Methods A total of 127 patients admitted to the Department of Neurology at Beijing First Hospital of In‐tegrated Traditional Chinese and Western Medicine between January 2022 and June 2025 for acute vertigo or dizziness were enrolled.Patients were classified into the VVD group(n=74)and the VN group(n=53)according to established in‐ternational diagnostic criteria.Demographic data,clinical symptoms and signs,vascular risk factors,ABCD2 scores,and laboratory parameters were collected and compared between groups.Results The age of the VVD group[(68.91±11.03)years]was higher than that of the VN group[(56.64±12.71)years],and the proportion of males(67.6%)was also higher than that of the VN group(45.3%)(all P<0.05).The prevalence rates of hypertension,diabetes,hyperlipid‐emia,hyperhomocysteinemia,prior cerebral infarction or transient ischemic attack,and alcohol consumption were higher in the VVD group than in the VN group(all P<0.05).The VVD group had a greater number of vascular risk factors[4.5(4,5)]and a higher ABCD2 score[5(4,6)]than the VN group[2(2,4)and 3(2,4),respectively](all P<0.001).The VN group had higher rates of vertigo,unsteadiness,and autonomic symptoms(all P<0.001),while visual disturbanc‐es were more common in the VVD group(P=0.036).Signs suggestive of central nervous system involvement:including dysarthria or dysphagia,central facial palsy,sensory deficits,limb weakness,ataxia,and gaze-evoked nystagmus were more common in the VVD group,whereas patients with VN predominantly exhibited unidirectional horizontal nystagmus(all P<0.05).Additionally,the VVD group had lower high-density lipoprotein cholesterol and low-density lipoprotein cho‐lesterol levels but higher homocysteine levels than the VN group(all P<0.05).Conclusions Age at onset,sex,burden of vascular risk factors,ABCD2 score,specific clinical manifestations,and select laboratory parameters are valuable for differentiating VVD from VN.These features may facilitate early identification of high-risk VVD patients and guide target‐ed diagnostic evaluation.
Keywords：vascular vertigodizzinessvestibular neuritisdifferential diagnosisrisk factorABCD2 score
Publication Date：2026-02-25
Online Publishing Date：2026-03-19(First online date of this platform, not the publication date of the document)
Pages：6( 21-26 )