Meta-analysis of influencing factors of activation levels in patients with chronic disease
ZHANG Tao
LI Jinxiu
DENG Libang
TIAN Yanzhen
ZHANG Shiji
FENG Nina
Abstract：Objective To explore the influencing factors of activation levels in patients with chronic disease.Meth-ods Literature on the influencing factors of activation levels in patients with chronic diseases were retrieved from databas‐es including CNKI,VIP,Wanfang,CBM,PubMed,and The Cochrane Library,with the search period spanning from the inception of each database to October 15,2024.After literature screening,data extraction,and quality assessment,Rev‐Man 5.3 software was used for meta-analysis.Results A total of 21 studies were included.The meta-analysis revealed that patients aged over 65 years(OR=0.98,95%CI:0.96-0.99,P<0.000 01),disease severity(OR=0.45,95%CI:0.22-0.93,P=0.008),comorbidities(OR=0.31,95%CI:0.19-0.50,P<0.000 01),anxiety and depression(OR=0.57,95%CI:0.36-0.90,P=0.02)were the negative factors for the activation level of patients with chronic diseases.While educational level(OR=10.98,95%CI:6.34-19.00,P<0.000 01),residing in the city(OR=8.94,95%CI:2.53-31.54,P=0.000 7),social support(OR=1.30,95%CI:1.19-1.43,P<0.000 01),health literacy(OR=1.26,95%CI:1.14-1.39,P<0.000 01),monthly household income per capita≥1 000 yuan(OR=25.26,95%CI:14.17-45.03,P<0.000 01),and long disease duration(OR=4.60,95%CI:2.35-8.99,P<0.000 01)were the promoting fac‐tors for the activation level of patients with chronic diseases.Conclusions Patient activation level in chronic disease pa‐tients is influenced by multiple factors.Age over 65 years old,educational level of high school or below,severe illness,living in rural areas,having complications,low health literacy,anxiety and depression,and a per capita monthly family in‐come<1 000 yuan are their negative factors,while social support and a long course of disease are their promoting factors.Healthcare professionals should dynamically assess patients'activation levels and implement targeted,individualized inter‐ventions to enhance activation,thereby improving self-management abilities and quality of life.
Keywords：chronic diseasepatient activationinfluencing factormeta-analysis
Publication Date：2026-02-25
Online Publishing Date：2026-03-19(First online date of this platform, not the publication date of the document)
Pages：7( 6-12 )