Research progress on the regulatory mechanism of Chinese herbal monomer intervention in bleomycin-induced pulmonary fibrosis animal model
SHI Yaonan
WANG Xuehui
Abstract：The cause of pulmonary fibrosis is unknown,progressive aggravation,gradual decline of lung function,and few clinical drugs for treatment.It was found that traditional Chinese medicine monomer can play a role in treating bleomycin-induced pulmonary fibrosis in animal model in the process of epithelial interstitial transformation and related sig-naling pathway,activation of autophagy,inhibition of macrophage polarization and inhibition of endoplasmic reticulum stress.
Keywords：pulmonary fibrosistraditional Chinese medicine monomerregulatory mechanismepithelial intersti-tial transformationautophagymacrophage polarizationendoplasmic reticulum stress
Publication Date：2024-08-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 64-68 )