Analysis of risk factors for frailty in elderly patients with Parkinson's disease
FAN Tingyong
HUANG Zhaojing
MENG Zhangmin
ZHANG Lulu
PENG Chunlan
Abstract：Objective To identify the risk factors associated with frailty in elderly individuals diagnosed with Parkin-son's disease.Methods A total of 147 elderly Parkinson's disease patients who were hospitalized in West China Hospi-tal of Sichuan University between September 2014 and February 2024 were selected.Based on their FRAIL score results,participants were categorized into frail and non-frail groups.Univariate analysis and binary logistic regression were employed to examine the risk factors for frailty in this population.Results Among of the 147 patients,58(39.4%)were identified as frail.Significant differences were observed in age,body mass index(BMI),D-dimer levels,platelet count,albumin levels,Barthel score,NRS,and Huaxi Fall Assessment scale between the frail and non-frail groups(all P<0.05).The binary logistic regression analysis indicated that BMI(OR=0.777,95%CI:0.679-0.889),albumin levels(OR=0.773,95%CI:0.773-0.933),Barthel score(OR=0.981,95%CI:0.967-0.995),and NRS(OR=1.529,95%CI:1.132-2.067)were significant factors influencing frailty in elderly Parkinson's patients(all P<0.05).Conclusions The preva-lence of frailty among elderly patients with Parkinson's disease is notably high.Factors such as low BMI,low albumin lev-els,low Barthel scores,and high NRS are identified as risk factors for frailty in this demographic.
Keywords：Parkinson's diseasefrailtyrisk factoraged
Publication Date：2024-08-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 14-17 )