Effect of hyponatremia on prognosis of elderly patients with novel coronavirus infection
ZHU Tong
JIANG Man
Abstract：Objective To investigate the effect of hyponatremia on prognosis of elderly patients with COVID-19 in-fection.Methods The clinical data of 151 patients with COVID-19 infection admitted to Shandong Provincial Hospital Affiliated to Shandong First Medical University from December 2022 to February 2023 were retrospectively analyzed.Pa-tients were divided into hyponatremia and normal natremia according to the blood sodium level at admission.Kaplan-Meier survival analysis was performed,and Log-rank test was used to compare the survival of the two groups.To compare the prognosis of elderly patients with COVID-19 infection with different clinical characteristics.Multivariate logistic regression was used to analyze the effect of hyponatremia on prognosis of elderly patients with COVID-19 infection.Results Among 151 elderly patients infected with COVID-19,56 cases were hyponatremia and 95 cases were normal natremia.Kaplan-Meier survival analysis showed that the overall survival of patients with hyponatremia was lower than that of those with nor-mal natremia(P=0.006).Multivariate logistic regression analysis showed that hyponatremia(OR=4.902,95%CI:1.453-16.537,P=0.010)was a prognostic factor in elderly patients with COVID-19 infection.Conclusion The surviv-al of elderly patients with COVID-19 infection complicated with hyponatremia is affected.
Keywords：COVID-19hyponatremiaprognosisintensive oxygen therapyinfluence factorelderly
Publication Date：2023-12-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 19-22 )