Wild-type transthyretin cardiac amyloidosis in an elderly male patient:a case report
Xiao ZOU
Hao WANG
Hong-Xiang YAO
Meng-Qi XU
Feng CAO
Zhi-Qing FU
Li SHENG
Abstract：Cardiac amyloidosis (CA) is characterized by the deposition of the misfolded amyloid precursor proteins in the myocardium of the heart. The systemic form of CA is mainly caused by either the misfolded monoclonal immunoglobulin light chains (kappa and lambda) or transthyretin. The clinical manifestations are mainly overlap with symptoms of other cardiovascular diseases mostly hypertrophic cardiomyopathy and heart failure. Some cases often overlooked and remains undiagnosed because of the atypical clinical manifestations, especially in the elderly. The incidence of CA has increased across the world recently. This paper reports the diagnosis and treatment of an elderly male patient with wild-type transthyretin CA (ATTRwt-CA). Combined with the standardized diagnosis procedure of CA, it can improve the understanding and diagnosis of CA among cardiovascular physicians.
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Publication Date：2025-12-30
Online Publishing Date：2026-01-09(First online date of this platform, not the publication date of the document)
Pages：4( 1001-1004 )