Re-evaluating drug-coated balloon use in the elderly:a need for comparative and stratified insights
Syeda Fadak Zahra Hujjat
Abstract：["I read with great interest the recent article by Shin, et al.[1] the authors present an important exploration in-to the use of drug-coated balloon (DCB) in patients aged ≥ 75 years, a demographic increasingly encountered in modern cardiovascular practice. The authors conducted a re-trospective analysis involving 2050 elderly patients (aged ≥ 75 years) undergoing successful percutaneous coronary inter-vention (PCI). Of these patients, 232 patients received DCB-based PCI (either DCB alone or in combination with drug-el-uting stent (DES), depending on lesion preparation) and were compared to 1818 patients treated with second-generati-on DES (DES-only PCI). Impressively, the DCB-based group showed significantly reduced stent burden and exhibit-ed a lower incidence of major adverse cardiovascular events at 2-year follow-up (5.5％ vs. 13.1％, P\u003d0.003), including lower rates of target vessel revascularization (1.1％ vs. 5.6％) and major bleeding (0.7％ vs. 5.1％). These findings highli-ght the clinical value of DCB in elderly cohorts, a group oft-en at higher bleeding risk and with greater frailty."]
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Publication Date：2025-10-30
Online Publishing Date：2025-11-19(First online date of this platform, not the publication date of the document)
Pages：1( 886 )