Research progress on the correlation between bone me-tabolism and chronic heart failure and osteoporosis
TANG Ya-jie
ZHANG Ying
HUANG Jun
WANG Da-ying
Abstract：Background Chronic heart failure (CHF) and osteoporosis (OP) are major health issues affecting the middle-aged and elderly population. With the intensification of population aging, the incidences of both conditions are increasing, severely affecting the quality of life of patients and the development of social medical care. In recent years, many studies have found a close relationship between the two conditions, with mutual influences, especially the impact of CHF on the risk and prognosis of OP, which has attracted increasing attention. Comprehensively understanding the risk of OP in heart failure patients and providing targeted interventions to prevent fractures is of great significance. However, the pathophysiological mechanisms of osteoporosis in patients with heart failure are not yet fully understood. A large number of recent studies have proven that, in addition to common risk factors (such as age, gender, blood lipids, smoking, etc.), there are still independent mutual connections between the two conditions. Domestic and international research has found that changes in cytokine or hormone levels in bone metabolism can affect the pathophysiological processes of CHF. Therefore, this article reviewed the correlation between bone metabolism and chronic heart failure and elderly osteoporosis, hoping to provide a reference for clinical treatment and prevention.
Keywords：Chronic heart failureOsteoporosisBone metabolism
Publication Date：2025-03-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 53-58,后插1 )