Diagnosis and treatment of adrenal hyperfunction in a dog
Wang Jie
Sun Huarun
Shen Shanshan
Xu Yanzhao
Sun Yawei
Abstract：Hyperadrenocorticism(HAC),also known as Cushing's syndrome,is a clinical disorder caused by chronic excessive secretion of glucocorticoids.As one of the most common endocrine diseases in dogs,it is easily misdiagnosed due to overlapping symptoms with other endocrine disorders.This report documents a case of a dog presenting with polyuria/polydipsia,generalized alopecia,and abdominal distension.Diagnostic tests,including complete blood count,C-reactive protein assay,blood biochemistry,adrenocorticotropic hormone(ACTH)stimulation test,low-dose dexamethasone suppression test,and abdominal ultrasonography,confirmed a diagnosis of HAC.The dog's condition was managed with Trilostane administration and supportive therapy.This case study aims to enhance understanding of the comprehensive diagnostic approach to canine HAC,explore improved treatment strategies,and alleviate animal suffering.
Keywords：Canine hyperadrenalACTH stimulation testDexamethasone inhibition testTrilostane
Publication Date：2025-04-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 59-63 )