Seroepidemiological investigation of hepatitis viruses in wild macaques in Guangxi
Hou Jiangning
Zhang Lujuan
Zeng Qi
Hu Liping
Long Limei
Xu Binda
Chen Qinyan
Abstract：This study aimed to investigate the prevalence of hepatitis A virus(HAV),hepatitis B virus(HBV),hepatitis C virus(HCV),and hepatitis E virus(HEV)infections in wild macaques in Guangxi.Serum samples from 67 wild macaques in a Guangxi nature reserve were tested for HAV-immunoglobulin M(IgM)antibodies,HEV-IgM antibodies,HCV antibodies,and HBV surface antigen(HBsAg)using enzyme-linked immunosorbent assay(ELISA).Nucleic acids of HAV,HBV,HCV,and HEV were detected using PCR fluorescent probe assays.Results showed that HBsAg and HCV antibodies were all negative.The positive rates for HAV-IgM and HEV-IgM antibodies were 1.49%(1/67)and 4.48%(3/67),respectively.No HAV,HBV,or HCV nucleic acids were detected,while HEV nucleic acid positivity was 1.49%(1/67).The study indicates that wild macaques in Guangxi can be infected with or carry HAV and HEV,but no HBV or HCV positive individuals were detected.
Keywords：Wild macaqueHepatitis virusSeroepidemiology
Publication Date：2025-03-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 63-65 )