Immuno-efficacy of inactivated PCV2 vaccine in mice
Zhu Guopo
Li Shaoli
Shao Panfeng
Wang Binqing
Li Xinhua
Abstract:To evaluate the immune efficacy of porcine cirovirus type 2 vaccine, the viral isola-tion method was used to get the minimum content of PCV2 which can infect all the Balb/c mice. Then, mice which had been immunized by inactivated vaccine were injected with this virus, and ana-lyzed the protective effect. Results showed that the minimum content of porcine circovirus type 2 can infect all the Balb/c mice is 106.5 TCID50/0.1 mL. The vaccine can protect the seven tenths of the mice with a viral content of 105.5 TCID50/0.1 mL, and reach to the immune effect. The research could provide an important reference data for improving the production process of existing vac-cine.
Keywords:Porcine circovirus type 2Viral isolationVaccine
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 33-36 )