Study on Extraction and Purification of Polygonum Lapathifolium Flavonoids
Zhu Yujing
Li Yan
Yu Zhijiao
Zhang Yong
Abstract：The present research studied the technoiogy of preparing and purified of flavonoids from Polygonum lapathifolium. With alcohol used as extraction solvent, flavonoids was extracted from leguminous Polygonum lapathifolium grazing by ultrasonic method. The final extracting condi-tions were optimized by the orthogonal experiment considering of extraction solvent, temperature of extraction, time of extraction and ratio of solid to liquid of extraction.. The yield of crude flavonoids from Polygonum lapathifolium is 10%, and content of crude flavonoids is 37% with the op-timum conditions: 80% alcohol, temperature 50℃, time 30 minutes, the ration of alcohol to materi-al 1:20. The macroporous absorption resin NKA-9 was selected as exclusive separation resin of fla-vonoids of Polygonum lapathifolium. The results shows: the better dynamic adsorption condition of Polygonum lapathifolium are concentration of sample 9-12mg/mL, pH 4-5, ration of diameter to height 1:10, the absorption velocity is limited in 1.25mL/min. With the conditions of the elution solvent is 70% ethanol under room temperature, the elution r velocity is 1.25mL/min. Under the con-dition the purity of Polygonum lapathifolium flavonoids up to 71%, 1 times of crude flavonoids.
Keywords：Polygonum lapathifoliumFlavonoidsExtractionPurification
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 9-14 )