Report on immune antibody monitoring of FMD in Bull
Yang Guoli
Cao Dong
Gu Zhida
Wang Jun
Wang Kecai
Zhao Fengju
Lan Desong
Abstract： To explore the immune effect of the currently used foot-and-mouth dis-ease virus(FMDV) type“O”and“Asian I”bivalent inactivated vaccine of bulls, We choosed a breeding oxen farm to carry out the tracking detection of the immune anti-bodies after vaccination. We gathered the serums of the immunized oxen every two months to detect the immune antibodies by liquid phase blocking ELISA in a period of 17 months, Meanwhile, according to the results of the detection of antibodies, we can scientifically evaluate the protection period aim to different kinds of bulls which injected by the same vaccine strain from a company, and investivate whether the immune antibodies have some relationship with the breed or age of the immunized bulls. The results showed that the antibodies levels with no relationship with the age of the bull; The immune antibodies level of type“O”is better than type“Asian I”; The immune response to the vaccine is different due to the genetic diverisity of different kinds of bulls, whereas the HS bulls had the lowest protection level after vaccination. Overall, the protection period can be maintained in 10 months after vac-cination of type“O”and“Asian I”bivalent inactivated vaccine of bulls.
Keywords：Breeding oxenFoot-and-mouth diseaseAntibodyfollowing detection
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 26-32 )