A case of malignant hidroacanthoma simplex on the hip
HE Lixia
LIU Yinghong
WENG Liqiang
LONG Qinqin
CHEN Borui
Abstract：We report a case of malignant hidroacanthoma simplex on the hip.An 85-year-old female presented with a 6-month history of a papule on her left hip.Dermatological examination showed a brown-colored hyperkeratotic plaque measuring 3 cm × 3 cm with irregular margins and visible surface crusts.Histopathological examination revealed marked hyperkeratosis,acanthosis,papillomatosis,and well-circumscribed intraepidermal tumor nests.Atypical cells with large,hy-perchromatic nuclei and mitotic activity were observed within the tumor nests.Immunohistochemi-cal staining was positive for EMA,CK14,CK20(a few cells),and Cam5.2(a few cells)in the lesional skin.The diagnosis was malignant hidroacanthoma simplex.Complete excision was per-formed,and no recurrence was observed during the 12-month follow-up period.
Keywords：hidroacanthoma simplexmalignant
Publication Date：2026-02-28
Online Publishing Date：2026-04-02(First online date of this platform, not the publication date of the document)
Pages：4( 138-141 )