Research progress on erythrodermic psoriasis
YANG Yingying
ZHONG Yuanqiu
LIU Fanghua
LIU Shougang
CHEN Yongfeng
Abstract：Erythrodermic psoriasis is a rare and unique type of psoriasis that often occurs in in-dividuals with a history of psoriasis.It can affect people of any age but is more common among middle-aged and elderly individuals.The incidence of erythrodermic psoriasis is relatively low worldwide.However,the specific incidence rate varies due to factors such as region and race.This review summarizes its epidemiology,pathogenesis(such as the activation of the Th17/IL-23 axis,and HLA-C*01:02 gene polymorphism),clinical diagnosis(such as biomarkers,IL-17A and CCL20),and treatment advancements(traditional drugs like methotrexate and new biological agents such as IL-17 inhibitors)related to EP.It also explores objective assessment methods for the severity of EP(such as PASI and DLQI scores)and future research directions(such as gene therapy).
Keywords：erythrodermic psoriasisautoimmune diseasesbiological agents
Publication Date：2025-10-28
Online Publishing Date：2025-11-20(First online date of this platform, not the publication date of the document)
Pages：8( 751-758 )