A case of acquired reactive perforating collagen disease with typical dermoscopic features
JI Juan
XU Haoxiang
SONG Hao
XU Changchun
Abstract：We report a case of acquired reactive perforating collagen disease with typical der-moscopic features.A 66-year-old woman presented with a 2-year history of generalized erythemas,papules,and itching,which had been aggravated for more than 2 months.Physical examination revealed a large erythema on the back,multiple keratinizing papules with central umbilical fovea in tan color.Erythemas,papules,scratches,and erosions were present on both lower extremities.A surgical scar about 10 cm long was visible on the right abdomen.(Back)Histopathology showed acanthosis,cup-like depression of the epidermis filled with parakeratotic debris,and necrotic col-lagen fibers penetrating the epidermis.Dermatoscopic examination revealed a central yellowish-brown amorphous area with a peripheral white halo,surrounded by pink amorphous area,along with reticular and linear blood vessels.Acquired reactive perforating collagenosis was diagnosed.After one-week treatments with oral Tripterygium wilfordii tablets,Olopatadine tablets,Levocetiri-zine tablets,and Pregabalin capsules,along with topical compounded Miconazole ointment and Polymyxin ointment,and phototherapy,rashes and erosions had basically healed and scabbed o-ver,with significant improvement in itching.After three weeks,a phone follow-up indicated par-tial resolution of the rashes,with itching mostly under control.
Keywords：reactive perforating collagen diseasedermatoscope
Publication Date：2025-10-28
Online Publishing Date：2025-11-20(First online date of this platform, not the publication date of the document)
Pages：5( 741-745 )