A case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluid
GUI Yu
CHEN Jiajie
YU Shuling
LIU Siqi
LIU Shengxiu
Abstract：We report a case of disseminated herpes zoster diagnosed by high-throughput se-quencing.A 74-year-old female presented with a one-week history of abdominal pain and disten-sion.Two months ago,she was diagnosed with ANCA-associated vasculitis and received immuno-suppressive therapy.One week ago,she developed unexplained abdominal pain.Pathogen DNA sequencing of ascitic fluid indicated varicella-zoster virus infection.Two days later,the patient de-veloped clustered hemorrhagic blisters with pain on her left lower limb.The patient was diagnosed with disseminated herpes zoster.Despite active treatment,the therapeutic response was unsatisfac-tory.The patient did not pursue further treatment and is currently lost to follow-up.
Keywords：disseminated herpes zosterstomachachehigh-throughput sequencing
Publication Date：2025-05-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 355-358 )