Progress in the diagnosis and treatment of mycosis fungoides with large cell transformation
DANGZENG Zhuoma
LIU Chenxi
WANG Tingting
Abstract：Mycosis fungoides is a non-Hodgkin lymphoma originating from skin-resident memo-ry helper T cells,representing the most common subtype of cutaneous T-cell lymphoma.Large cell transformation is a unique form of primary cutaneous T-cell lymphoma with unclear etiology and pathogenesis.Clinical manifestations and auxiliary examinations lack specificity.Whether patients need aggressive treatment is controversial.This article systematically reviews the etiology,patho-genesis,clinical manifestations,diagnosis,treatment,and prognosis of mycosis fungoides with large cell transformation,offering insights for its diagnosis and management.
Keywords：mycosis fungoideslarge cell transformation
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 716-720 )