A case of primary cutaneous marginal zone B-cell lymphoma
HUANG Jiamin
SUN Zhaojun
REN Haiyue
Abstract：We report a case of primary cutaneous marginal zone B-cell lymphoma.A 23-year-old male presented with red nodules on his back for 5 years.Physical examination revealed multi-ple demarcated red nodules on the back,sized 5 mm × 5 mm to 10 mm × 15 mm,with smooth sur-face,soft texture,but without scales and tenderness.Histopathology showed nodular lymphoid hy-perplasia in the dermis and subcutaneous tissue,partial follicular atrophy,and small-to medium-sized centrocytoid and monocytoid cells surrounding the follicles and eccrine glands,which locally infiltrated into the subcutaneous adipose tissue.Immunohistochemistry revealed positive for CD20,CD21(FDC network),CD23(FDC network),kappa,Bcl-2,CD43(partially),Ki-67(10％),and negative for CD3,CD4,CD5,CD8,Lambda,Bcl-6 and Cyclin-D1.The diagnosis was pri-mary cutaneous marginal zone B-cell lymphoma.The patient declined the treatment and was lost follow-up 1 year later.
Keywords：lymphomaB-cellmarginal zone
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 705-709 )