Bowen's disease of toe treated with plasma combined with photodynamic therapy:A case report and literature review
XU Rong
ZHAO Li
HOU Wenjun
LI Zhiyu
Abstract：A case of Bowen's disease of toe is reported.A 39-year-old woman presented with red asymptomatic lesion on the medial side of the left big toe for over a month.Topical treatment with glucocorticoid was not effective.A similar rash appeared on the same area 5 to 6 years ago,and was surgically removed.Clinical examination revealed a demarcated red plaque 1.5 cm × 1.5 cm in diameter,with dark red crust in the center,on her big left toe.The histopathological exami-nation of the skin lesion showed heteroplasia of the squamous epithelium in the epidermis.The di-agnosis was Bowen's disease.Following removal of lesion with electrocauterization,5-aminolevu-linic acid photodynamic(ALA-PDT)was given 4 times.The lesion completely subsided with no re-currence during 1-year telephone follow-up.
Keywords：Bowen's diseasetoeplasma5-aminolevulinic acid photodynamic
Publication Date：2024-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 407-412 )