Clinical observation of trephine combined with superficial X-ray radiation and local injec-tion in the treatment of generalized keloids
LIU Liuhong
ZHAN Jipang
ZHONG Jing
WANG Weijia
MI Ciren
LIN Aiqing
ZHU Dingheng
HE Renliang
Abstract：Objective To evaluate the clinical efficacy and safety of trephine combined with superficial X-ray radiation and local injection in the treatment of generalized keloids.Methods Five patients with generalized keloids treated at Dermatology Hospital of Southern Medical Univer-sity from May 2020 to May 2021 were included in this study.VSS scores were compared before and after 12-month treatments with trephine combined with superficial X-ray radiation and local in-jection of triamcinolone acetonide.Adverse reactions were also assessed.Results After the treat-ment,all scar tissue became flatter and softer.The VSS scores were significantly decreased from the baseline(4.08±1.11 vs.9.28±1.52,t=16.30,P＜0.001).No severe infections,severe allergy or skin ulcers were observed during the follow-up period.Conclusion Trephine combined with superficial X-ray radiation and local injection of triamcinolone acetonide is effective and safe for keloids.
Keywords：trephinesuperficial X-ray radiationlocal injectionkeloidgeneralized
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 232-236 )