Update on DNA methylation in UV radiation-related skin diseases
CHEN Wenting
ZHONG Xinni
LI Wei
Abstract：DNA methylation is a common epigenetic phenomenon that changes genetic expres-sion without altering the DNA sequence.With deepening research on DNA methylation,more and more variable positions of methylation have been identified in a variety of diseases(such as tumors,diabetes and neurological disorders).Ultraviolet(UV)radiation is an important environmental factor for skin damage and aging.DNA methylation is involved in the occurrence and development of UV radiation-related skin conditions and diseases.In this paper,we review the research pro-gress of DNA methylation in UV radiation-related skin diseases,such as solar dermatitis,actinic keratosis,skin tumor,lupus erythematosus and photoaging,in order to provide new ideas for sub-sequent research in UV radiation-related skin diseases.
Keywords：DNA methylationepigeneticssolar dermatitisactinic keratosispho-toaging
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 561-566 )