Eccrine porocarcinoma of the toe:A case report
ZHAO Wenjun
MI Xinling
WANG Kun
LIU Dongmei
HUANG Chiqing
XU Gongjun
Abstract：A case of eccrine porocarcinoma on the toe is reported.A 67-year-old female pres-ented with a 3-year history of infiltrated plaque on the left middle toe.Physical examination showed a hard infiltrated plaque covered with crusts in reddish brown color,with broken nail,ele-vated borders and blurry boundaries,on the nail bed of the left middle toe.Histopathological find-ings included a demarcated tumor connected to the epidermis with growth towards the dermis,tumor necrosis,large pleomorphic cells with vacuoles and large hyperchromatic nuclei,multinu-cleated giant cells,pathological mitosis and various degree of ductal differentiation.Immunohisto-chemistry showed positive for CK7,EMA,CK5/6,p16,p40 and p63,and 60％～90％of Ki-67 positive.The diagnosis was eccrine porocarcinoma.Lesion was removed by Mohs microsurgery,and the follow-up is ongoing.
Keywords：eccrine porocarcinomatoe
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 554-557 )