Clinical Analysis on 35 Cases of Dermatofibrosarcoma Potuberans
SUN Kai-liang
CHEN Hui
LI Yu-mei
ZHOU Chun-hong
WAN Miao-jian
LI Hua
WU Tao
Abstract：Objective:To discuss the clinical characteristics , sonographic findings , surgical treatment and pathological diagnosis and differential diagnosis of dermatofibrosarcoma protuberans ( DFSP) .Methods:35 cases of DFSP were analyzed retrospectively .The clinical features , ultra-sonic features , histopathological features , treatment and prognosis were retrospectively analyzed . Results:There were 22 males and 13 females , the average age of the patients were ( 35.4 ± 12.4) years old.Typical clinical manifestation included skin patches , plaques or nodules, and without ulcer .The involved area in most patients is the trunk .Histopathological characteristics for the consistency of spindle tumor cells showed storiform or radial wheel-like arrangement , infiltra-tive growth, focal prominent atypic tumor cells , similar to changes in fiber sarcomatoid tumor . Tumor cells expressed vimentin .There were one case of recurrence in this group of patients with MMS after 1 year, and 2 cases after 3 years.Conclusion:DFSP has multiplex clinical manifesta-tions and was easily to be misdiagnosed .It can be further confirmed by tissue pathology and im-mune group examination .MMS is the first choice in its treatment .
Keywords：Dermatofibrosarcoma protuberansClinical manifestationUltrasonographyMMS surgeryPathological characteristics
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 367-371,375 )