Clinical Analysis on 28 Cases of Pityriasis Lichenoides et Varioliformis Acuta
HUANG Li-ning
LUO Guang-pu
XUE Ru-zeng
GU Mei
LIU Hong-fang
WU Tie-qiang
CHEN Yong-feng
GU You-shou
YANG Bin
Abstract：Objective:To explore the clinical features and treatment of pityriasis lichenoides et varioliformis acuta ( PLEVA) .Methods:Retrospective analysis was performed on the clinical data of 28 patients with PLEVA .Results:The mean age of 28 patients (18 males and 10 females) was 23.9 ±6.25 years with a peak of 10 to 20 years.The clinical course was from 15 days to 24 months.The clinical features of PLEVA were hemorrhagic necrotic papules and varioliform scars . In lesion distribution , the majority of lesions were located on the trunk and limbs .The histopatho-logical features include apoptotic keratinocytes , liquefaction of basal cells , top-heavy and wedge-shaped lymphocyte infiltration .Oral tetracycline or erythromycin is the most effective treatment regimens.If necessary tripterygium wilfordii and methotrexate could be added .Topical corticoste-roids, topical calcipotriol , PUVA ( psoralen plus UVA ) and narrowband ultraviolet B phototherapy could be good choices .Most patients achieved remission within 2 to 3 weeks after the combination treatment regimens described above , presenting as reduced number of lesions and varioliform scars.Conclusion:The diagnosis of PLEVA requires close correlation of clinical features with path-ological presentation .Appropriated treatment regimen will shorten the clinical course .
Keywords：Pityriasis lichenoidesvarioliformisacutaClinical featuresTreatment
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 380-382 )