The Survey of Prevalence of Metabolic Diseases and the Assessment of Insulin Resistance in Psoriasis Patients
LI Ying
WANG Liu-yuan
LI Yuan
YANG Bin
Abstract：Objective:To survey the prevalence of metabolic diseases in psoriasis patients , and to evaluate the condition of insulin resistance in psoriasis patients .Methods:The proportion of metabolic diseases in 180 psoriasis patients and 200 normal subjects were analyzed .Fasting blood glucose and insulin levels in 70 psoriasis patients and 40 control subjects randomly selected from the above population were determined by glucose oxidase and chemiluminescence methods , re-spectively .IR index was calculated using the steady state model of HOMA .Results:The propor-tion of hypertension ( OR=2.39 ) , type 2 diabetes ( OR=4.27 ) , hyperlipidemia ( OR=2.21 ) , obesity ( OR=3.04 ) and metabolic syndrome ( OR =5.21 ) associated with psoriasis in patients group was statistically higher than that of normal controls (P<0.05).The proportion of heart dis-eases between the two groups was not statistically significant (OR=1.11,P>0.05).IR index in psoriasis group was significantly higher than that in control group [ 2.54 ( 0.62 ~28.71 ) vs 2.01 (0.56~6.39),P<0.05].Conclusion:The proportion of metabolic diseases in psoriasis patients is higher than that of normal controls .Psoriasis patients have insulin resistance , and insulin resist-ance index is higher than that of normal controls .
Keywords：PsoriasisMetabolic diseaseInsulin resistance
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 318-320 )