Progress in the application of copper sulfide nanomaterials for the diagnosis and treatment of cancer
DIAO Xinyue
FANG Jinhai
YAO Jun
Abstract：In recent years,nanomaterials have demonstrated unique advantages in thermal,optical,and electrical properties due to their distinctive size effects and surface effects,offering new opportunities for tumor diagnosis and treatment.Copper sulfide(CuS)nanomaterials exhibit significant potential in antitumor research owing to their favorable biocompatibility,efficient Fenton-like catalytic activity,and excellent photothermal conversion performance.Through the synergistic combination of photothermal therapy and chemodynamic therapy,CuS nanomaterials can substantially enhance therapeutic outcomes.Furthermore,these materials can serve as drug delivery carriers,loading chemotherapeutic agents,photothermal agents,photosensitizers,and immune activators to achieve multimodal combination therapy,thereby further improving treatment efficacy.This article systematically reviews recent advances in the application of CuS nanomaterials in tumor therapy,with a focus on their roles in photothermal therapy,chemodynamic therapy,chemotherapy,photodynamic therapy,gas therapy,immunotherapy,and tumor diagnosis.On this basis,current challenges are analyzed,and future development directions are prospected.
Keywords：copper sulfide nanomaterialsnanomedicinetumortreatmentdiagnosis
Publication Date：2026-01-28
Online Publishing Date：2026-03-18(First online date of this platform, not the publication date of the document)
Pages：5( 105-109 )