Clinical analysis of totally laparoscopic digestive tract reconstruction in radical resection for colon cancer
CUI Yongxin
LIANG Xu
LIAN Jiayu
BAI Junwei
Abstract：Objective To investigate the application and clinical outcomes of totally laparoscopic digestive tract reconstruction in radical resection for colon cancer.Methods A total of 102 colon cancer patients who underwent surgical treatment at Zhoukou Central Hospital between March 2021 and March 2024 were selected.According to the method of digestive tract reconstruction,they were divided into two groups:the observation group(n=49)underwent totally laparoscopic intestinal anastomosis,and the control group(n=53)underwent intestinal anastomosis via an auxiliary incision.The surgical approach for all patients was based on the Chinese Protocol for Diagnosis and Treatment of Colorectal Cancer,combined with preoperative assessment and tumor pathological characteristics.Clinical data were retrospectively analyzed,including perioperative indicators,visual analogue scale(VAS)pain scores on postoperative days 1,3,and 7,postoperative recovery,levels of diamine oxidase(DAO),D-lactate(DLA),and glutamine(Gln)before and after surgery,gastrointestinal quality of life index(GIQLI)scores,prognostic nutritional index(PNI),and the incidence of postoperative complications.Results The incision length in the observation group was significantly shorter than that in the control group[(3.21±0.52)cm vs.(6.33±1.02)cm,t=19.222,P＜0.001].There were no statistically significant differences between the two groups in operative time,intraoperative blood loss,or number of lymph nodes harvested(P＞0.05).The VAS scores on postoperative days 1,3,and 7 in the observation group were 4.62±1.08,2.66±0.51,and 1.55±0.52,respectively,all significantly lower than those in the control group(5.83±1.12,3.34±0.57,and 1.96±0.43)with statistically siginificant differences(t=5.546,6.330,4.352,all P＜0.001).The time to first flatus,defecation,ambulation,incision healing,and hospital stay were all shorter in the observation group compared to the control group(all P＜0.05).Postoperatively,DAO and DLA levels increased in both groups compared to preoperative levels,but were lower in the observation group.Gln levels decreased in both groups,but were higher in the observation group(all P＜0.05).After 6 months of follow-up,GIQLI scores improved and PNI scores decreased postoperatively in both groups compared to preoperative values(P＜0.05),with no statistically significant difference between the groups(P＞0.05).The incidence of postoperative complications in the observation group was 4.08％(2/49),significantly lower than the 18.87％(10/53)in the control group(x2=5.363,P＜0.05).Conclusion In radical resection for colon cancer,the application of totally laparoscopic digestive tract reconstruction offers advantages including minimal invasiveness,less postoperative pain,faster recovery,a lesser impact on intestinal barrier function,and a lower incidence of complications.
Keywords：colon cancerlaparoscopydigestive tract reconstructionclinical effect
Publication Date：2026-01-28
Online Publishing Date：2026-03-18(First online date of this platform, not the publication date of the document)
Pages：6( 86-91 )