Comparison of the therapeutic effects between endoscopic and open modified radical mastectomy for breast cancer
SPU Zhuo
ZHAO Xiaobo
ZHOU Shuang
Abstract：Objective To explore the clinical efficacy and safety of modified radical mastectomy and open surgery for breast cancer under laparoscopy.Methods A retrospective analysis was conducted on a total of 160 female patients who underwent modified radical mastectomy for breast cancer in the Affiliated Hospital of North Sichuan Medical College from January 2021 to January 2025.They were divided into the endoscopic group(n=60)and the open group(n=100)according to the surgical methods.Compare the differences between the two groups of patients in terms of perioperative indicators,postoperative complications,postoperative quality of life and clinical efficacy.Results There were no statistically significant differences in baseline characteristics such as age,gender,BMI,tumor size,number of sentinel lymph nodes,TNM stage and menstrual status between the two groups of patients(P>0.05).The operation time[(67.2±11.7)min vs.(92.1±10.6)min],intraoperative blood loss[(57.8±11.5)mL vs.(40.1±9.6)mL],and drainage volume[(1 605.7±275.6)mL vs.[(865.7±131.6)mL],drainage time[(8.7±2.9)d vs.(7.0±1.9)d],incision length[(21.4±3.9)cm vs.(8.6±1.5)cm]and postoperative hospital stay[(4.1±1.2)d vs.(3.5±1.1)d]were statistically significant(P<0.05).The total incidence of postoperative complications in the endoscopic group was significantly lower than that in the open group(6.7%vs.19.0%,P<0.05).The patient was followed up for 6 months after the operation In the endoscopic group,patients had pain scores on the affected upper limb[(6.5±1.5)points vs.(8.7±1.4)points],chest wall pain scores[(7.0±1.7)points vs.(8.9±0.9)points],and shoulder joint range of motion scores[(7.6±1.2)points vs.(8.7±1.3)points]and arm activity function score[(7.7±1.4)points vs.(8.9±0.9)points]were significantly better than those in the open group(P<0.05).At the end of the follow-up,there was no statistically significant difference between the two groups of patients in clinical efficacy indicators such as survival rate,local recurrence rate and distant metastasis rate.Conclusion Compared with open surgery,modified radical mastectomy for breast cancer by laparoscopy has significant advantages in perioperative indicators,postoperative complications and postoperative quality of life,and the clinical efficacy is comparable.
Keywords：breast canceropen surgeryendoscopymodified radical mastectomy
Publication Date：2025-12-28
Online Publishing Date：2026-01-12(First online date of this platform, not the publication date of the document)
Pages：5( 1208-1212 )