Research progress of zeolitic imidazolate framework-8-based nanomaterials in tumor therapy
FANG Jinhai
DIAO Xinyue
YAO Jun
Abstract：In recent years,the incidence of tumor continues to rise worldwide,and it has become the second leading cause of human death.With the rapid progress of nanotechnology,metal-organic frameworks have demonstrated great potential in the field of cancer therapy due to their high porosity,adjustable pore size,and easy functionalization.In particular,zeolitic imidazolate framework-8(ZIF-8)has attracted much attention in medical applications due to its low toxicity and excellent biocompatibility.Nanomaterials based on ZIF-8 have great application prospects in chemotherapy,chemodynamic therapy,phototherapy,sonodynamic therapy,immunotherapy,gene therapy,and ion interference therapy.This review summarizes the research progress of ZIF-8 based nanomaterials in tumor therapy,and prospects for the future development direction.
Keywords：TumorNanomaterialsMetal-organic frameworkZeolitic imidazolate framework-8Drug delivery sys-tems
Publication Date：2025-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 407-413 )