Exploration on the safety method of intravenous infusion of trilaciclib
ZHOU Shanshan
YANG Jinchun
YAO Yiying
WANG Yalan
Abstract：Objective To explore the safety method of intravenous trilaciclib infusion.Methods A safety protocol of intravenous infusion of trilaciclib was applied on 26 patients with small cell lung cancer from April 2023 to February 2024.The protocol included vascular assessment,vascular selection,health education,sectional preventive medication,infusion site observation,symptomatic treatment,health education and post-infusion follow-up.Phlebitis occured after the infusion of trilaciclib was monitored.Results Among the 26 patients,8 patients infused through the infusion port without phlebitis.For 18 patients received peripheral intravenous infusions,5 of them developed phlebitis.One patient appeared sectional redness and swelling,and 4 patients manifested as sectional induration formation and mild pain when pressing.The continuous use of mucopolysaccharide polysulfate reduced the redness,swelling and the scope of induration,as well as relieved the pain of the patients.Conclusion Implement the safety protocol throughout the infusion of trilaciclib may reduce the incidence and severity of phlebitis,thus relieving the pain of patients,and ensuring the smooth progress of the chemotherapy plan.
Keywords：Small cell lung cancerTrilaciclibPhlebitis
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 791-796 )