Clinical observation of endoscopic submucosal dissection,transparent hat mucosal resection and mucosal multi ring ligation resection for early esophageal cancer
LV Kunyu
JIA Yuhao
LI Yiying
LIU Zhiqiang
LI Baozhong
Abstract：Objective To investigate the efficacy of endoscopic submucosal dissection(ESD),transparent cap mucosal resection(EMR-Cap),and mucosal multi ring ligation resection(MBM)in the treatment of early esophageal cancer and precancerous lesions.Methods A retrospective analysis was conducted on 246 patients with early esophageal cancer and precancerous lesions who underwent endoscopic treatment in our hospital from December 2017 to December 2021.Among them,84 patients received ESD treatment(ESD group),70 patients received EMR-Cap treatment(EMR-Cap group),and 92 patients received EMBL treatment(MBM group).Kaplan-meier method was used to draw survival curves.Results The incidence of postoperative complications in the EMR group,EMR-Cap group,and MBM group was 15.48%,12.86%,and 8.70%,respectively,with no statistically significant difference(P＞0.05).There was no statistically significant difference in 1-year,2-year recurrence free survival,1-year,2-year,and 3-year local lymph node metastasis free survival,and 1-year distant metastasis free survival among the three groups of patients after surgery(P＞0.05);There was a statistically significant difference in the 3-year recurrence free survival rate among the three groups of patients after surgery(P＜0.05);There was a statistically significant difference in the 2-year and 3-year distant metastasis free survival rates among the three groups of patients after surgery(P＜0.05).In the ESD group,there were 6 deaths due to lymphatic metastasis during follow-up,with a mortality rate of 7.14%(6/84);In the EMR-Cap group,there were 5 deaths due to lymphatic metastasis,with a mortality rate of 7.14%(5/70);There were 4 deaths due to lymphatic metastasis in the MBM group,with a mortality rate of 4.35%(4/92).The Kaplan-meier method showed no statistically significant difference in survival time among the three groups of patients(P＞0.05).Conclusion ESD,EMR-Cap,and MBM are all effective treatment method for early esophageal cancer and precancerous lesions.In clinical practice,surgical treatment plans can be selected based on the patient's specific condition to improve their quality of life.
Keywords：Early esophageal cancerPrecancerous lesionsEndoscopic submucosal dissectionTransparent cap mucocalectomyMucosal polyclinectomy
Publication Date：2023-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 940-944 )