A comprehensive review of interval breast cancer of screening programs

ZHANG Na; SUN Yuanjue.

Abstract：Screening, as the secondary prevention of disease, aims to improve the prognosis by early detection, diagnosis and treatment at the preclinical stage of the disease. Breast cancer screening is an effective, simple and economical way to screen asympto?matic women. Its ultimate goal is to reduce breast cancer mortality. Most scholars at home and abroad have recognized the role of mam?mography screening in reducing the mortality of women over 40 years old with breast cancer. In 2019, Shanghai anti?cancer association issued recommendations for screening and prevention of common malignancies in residents. It recommended women at average risk get mammograms every other year, starting at the age of 35; Mammography every 1?2 years for the age of 40 and older; Mammograms should be done every two to three years after the age of 60. Interval breast cancer is also caused by screening. Compared with breast cancer detected by screening, interval cancer is generally considered to be more invasive and have a worse prognosis. In order to fully understand its clinicopathological features and prognosis, and to provide clues on how to improve the benefit of screening, the following review is made on interval breast cancer.