Effects of intensity-modulated radiotherapy using linac with different width of MLC in lung cancer
YE Liuqing
HONG Wensong
LI Zhen
HUANG Kailing
HUANG Zhaohui
Abstract：Objective To compare the dosimetric characteristics of two different width of multi leaf collimator (MLC) on intensity-modulated radiotherapy (IMRT) planning of lung cancer.Methods From March 2016 to March 2017,a total of 20 patients with stage Ⅳ lung cancer receiving concurrent IMRT with chemotherapy were enrolled.Pinnacle3 V9.2 TPS was applied with Siemens Artiste with 5 mm MLC or Varian CX with 10 mm MLC.The volume of heterogeneity index (HI),conformal index (CI),maximum dose,minimum dose,average dose and the index of organs at risk of volume histogram were compared.Results The CI of Siemens Artiste of 5 mm MLC was 0.88±0.02,better than 0.85±0.03 of Varian CX of 10 mm MLC,and the difference was statistically significant(P=0.04).No significant difference was observed in HI (1.06±0.01 vs.1.06±0.01),maximum dose[(64.54±6.10) Gy vs.(64.59±6.00)Gy] and minimum dose [(51.60±5.94)Gy vs.(51.29±5.66) Gy] between 5 mm MLC and 10 mm MLC planning.For the organ at risk,lung V5,lung V20,the mean dose of lung,the mean dose of heart and the maximum dose of spinal cord had no significant different (P＞0.05).Conclusion The Siemens Artiste with 5 mm MLC can improve the target conformal in the IMRT planning of lung cancer.
Keywords：Lung cancerMulti leaf collimator (MLC)Leaf widthIntensity-modulated radiotherapy (IMRT)
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1035-1037 )