Progression on the mechanism of PRL-3 in tumors
SONG Xiujun
LIU Jianhong
LV Jin
Abstract：Phosphatase of regenerating liver-3 (PRL-3) is a metastasis-associated phosphatase which was highly expressed in various types of cancers, such as acute myeloid leukemia, colorectal cancer, breast carcinoma, non-small cell lung cancer and so on.It can promote cell proliferation, migration and invasion.In recent years, with the development of research methods,the research on mechanism of PRL-3 in tumor is increasing.These studies found that the pathways of tumorigenesis and metastatic was not all the same in deferent tumors.So it has the wide prospect of the clinical application in targeted therapy.This review is about the mechanism of action of PRL-3 in tumors.
Keywords：TumorPhosphatase of regenerating liver-3(PRL-3)Mechanism
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 566-569 )