The feasibility of the detection of circulating tumor cells by Celltracks(R) AutoPrep(R) system
HAN Lu
LI Sheng
WANG Zhenping
CUI Kai
Abstract:At present, more and more research indicates that Celltracks(R) AutoPrep(R) misses circulating tumor cells(CTCs)with atypicalepithelial characteristics,which have a stronger ability of invasion and metastasis than CTCs simply expressing epithelial characteristic and a higher value to judge efficacy and prognosis. This paper reviews the contrast between Celltracks AutoPrep system and ISET technology,and the effect of EpCAM expression, hybrid,EMT+tumor,circulating tumor stem cells and irreversible EMT+tumor cells on the detection rate of Celltracks(R) AutoPrep(R)system,as well as the feasibility of Celltracks(R) AutoPrep(R) system for detecting CTCs.
Keywords:Celltracks(R) AutoPrep(R) systemCirculating tumor cells (CTCs)Epithelial-mesenchymal transition(MET)
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 465-468 )
