Research progress of CD20 negative diffuse large B cell lymphoma
SUN Mengqi
ZHAO Shu
ZHANG Qingyuan
Abstract：The CD20-negative diffuse large B-cell lymphoma (DLBCL) is a rare and heterogeneous group of lymphoproliferative disorders.Given the lack of CD20 expression, atypical cellular morphology and aggressive clinical behavior characterized by chemotherapy resistance and inferior survival rates, CD20-negative DLBCL represented a challenge from the diagnostic and therapeutic perspectives.This review introduces the clinical characteristics, prognosis and treatment of different types of CD20-negative DLBCL to improve clinicians` awareness for this kind of malignancy and to enhance its therapeutic effect.
Keywords：Diffuse large B-cell lymphoma(DLBCL)CD20 negativePlasmablastic lymphomaPrimary effusion lymphoma
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 461-464 )