Clinical observation of ⅠE stage non?conjunctival primary ocular adnexal mucosa associated lymphoid tis?sue lymphoma( POAML) treated with radiotherapy
ZHAO Shuixi
CAO Jingxu
XIAO Lihua
Abstract：Objective To evaluate dose effect and prognosis of radiotherapy forⅠE stage non?conjunctival primary ocular ad?nexal mucosa associated lymphoid tissue lymphoma (POAML). Methods The data of 33 patients (42 eyes) with non?conjunctival POAML from Nov. 2003 to Mar. 2012 were retrospectively analyzed. Results When the irradiation doses were 18 Gy and 27 Gy, the remission rates of WHO criteria were 31% and 429% ( P=0258) , respectively. The remission rates of RECIST criteria were 286%and 381% ( P=0355) , respectively. Thirty?three patients with local control rate was 100%. The 5?, 10?year survival rates and dis?ease?free survival rate of the patients were 968%, 847% and 896%, 896%. The 5?,10?year survival rates of patients received 306 Gy and 27 Gy were 100%, 957%, 80% and 957% ( P=08578 ); 5 years and 10 years disease?free survival rates were 833%, 911%, 833% and 911% ( P=06497) . Conclusion Non conjunctiva POAML is sensitive to radiotherapy. 27 Gy irradia?tion dose can achieve better local control and long?term survival. Exploring the optimal dose of radiation requires a prospective large dose effect study.
Keywords：Mucosa associated lymphoid tissue lymphomaOcular adnexal lymphomasRadiation therapyDose re?sponse
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 66-69 )