The relationship between 18F?FDG PET/CT metabolic parameters and clinicopathological factors of colorectal cancer
DING Chongyang
LI Tiannv
SUN Jin
Abstract：Objective To investigate the correlation between metabolic parameters of 18 F?FDG PET/CT and clinicopathologi?cal features of colorectal cancer( CRC) . Methods The study comprised 84 patients with colorectal cancer. All patients were underwent 18 F?FDG PET/CT before surgery. Maximum standardized uptake value( SUVmax ) , mean standardized uptake value( SUVmean ) and meta?bolic tumor volume(MTV) of primary lesion were measured, and total lesion glycolysis(TLG) was calculated. Relationship between metabolic parameters and clinicapathological factors was analyzed. Results SUVmax , SUVmean , MTV and TLG of 84 primary lesions were 1179(536,2948), 711(310,1951), 1467(322,5477) cm3 and 9647(1318,93693) g, respectively. SUVmax, SUVmean, MTV and TLG were related to the tumor location, differentiation degree and the maximum diameter(P<005).T stage were both positively correlation with all metabolic parameters( r=0318,r=0281,r=0390,r=0416,P<005) . Only the TLG was posi?tively correlation with clinical stage( r=0355,P=0001) . Conclusion Metabolic parameters of CRC primary lesion have good corre?lation with clinicopathological factors, and can reflect partial characteristics of the tumor pathology in a certain extent.
Keywords：Colorectal neoplasmPositron emission computed tomographyX?ray computed tomography(CT)Deoxyglucose
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 53-57 )