Impact of microenvironment on immunotherapies in gastric cancer
WANG Xiaolu
JIANG Jingting
WU Changping
Abstract：Gastric cancer is one of the malignant tumors with high mortality of digestive system. At present, the main treat-ment methods of gastric cancer are surgical resection, radiotherapy and chemotherapy, however, the outcome is not as good as expec-ted. Along with the rapid development of immunology, cancer immunotherapy has become a research hotspot. Immunotherapies such as tumor vaccine and immune checkpoints targeted therapy have exhibited a promising prospect. Because of the complex pathogenesis and heterogeneity of gastric cancer, many problems still remain to be solved. Tumor microenvironment plays an important role in tumor oc-currence, development and metastasis. This article reviews the research achievements, problems and prospects of tumor microenviron-ment and immunotherapies for gastric cancer.
Keywords：Gastric cancerTumor microenvironmentImmunotherapy
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1038-1042 )