Progress in revealing the immunological mechanisms behind the anti-tumor activity of oxaliplatin
GONG Xinlei
YANG Liuqing
QIN Shukui
Abstract：Oxaliplatin is the third-generation platinum compound with the some advantages of high efficiency, low toxicity and difficult to resistant etc, thus obviously different from other first-and second-generation platinum drugs. Recent studies have shown that in addition to cytotoxic effect of oxaliplatin that is direct action in cancer cell DNA, immunological mechanism is a new and very impor-tant aspect of its anti-tumour effect. Thus this paper want to briefly review the study progression of immunological mechanisms in oxali-platin anti-tumour effect and its clinical implications,to help oncologists understanding related issues and expanding treatment as well as research thought.
Keywords：Anti-tumour effectOxaliplatinImmunological mechanismsStudy progression
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 1031-1037 )