Impacts of rectum filling status on dosimetric parameters of target volume and organ at risk in intensity-modulated radiotherapy for prostate cancer
YING Wenmin
LIAO Shaoguang
FU Zhichao
FENG Jing
LEI Yong
CHENG Huihua
Abstract：Objective To investigate the impact of rectum filling status on the dosimetric parameters of target volume and or?gan at risk ( OAR) in intensity?modulated radiotherapy ( IMRT) for patients with prostate cancer. Methods Fifteen patients with prostate cancer were enrolled in this study. Target and OAR were contoured by the same doctor both when the rectum was full and emp?ty. And the IMRT plan was designed by the same medical physicist at the same radiotherapy dose. The impact of rectum filling status in dose of target and OAR during radiotherapy was investigated. Results If the rectum filling status was consistent in orientation and radi?ation, the rectum fill status was not associated with the dosimetric parameter of target volume and bladder, femoral heads (P>0?05). If the rectum filling status was not consistent in orientation and actual radiation, the dosimetric dose, uniform index and conformal index of target were different( P<0?05) . The impacts on bladder and femoral heads were not significant. Conclusion To guarantee the per?fect execution of IMRT in patients with prostate cancer, it is recommended to keep the same rectal filling status during orientation and actual radiation.
Keywords：Prostate cancerIntensity-modulated radiotherapy(IMRT)Volume and position changes of rectumOrgan at risk(OAR)Dosimetry
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 810-813 )