Research progress of tumor-infiltrating lymphocytes in triple-negative breast cancer
FANG Hehui
YANG Fang
GUAN Xiaoxiang
Abstract：Triple-negative breast cancer( TNBC) is a heterogeneous disease. It is often characterized by the lack of specific therapeutic molecular targets and poor prognosis. There are increasing evidences about the relationship between tumor-infiltrating lym-phocytes and the prognosis of TNBC. However, the distinction between different types of T lymphocytes is extremely important, because of their different roles in the tumor microenvironment. Moreover, tumor-associated macrophages have been associated with a relatively poor outcome in TNBC. In this article, we review the role of different lymphocyte infiltration in the clinical outcome of TNBC.
Keywords：Tumor-infiltrating lymphocytesTriple negative breast cancerTumor-associated macrophagesPrognosis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 650-653 )