Application of percutaneous coaxial core needle biopsy via director assisted CT guidance in retroperitoneal lymphomas

FENG Weijian; WU Xiangrong; YANG Linfeng; YAO Jie; FANG Hua; WEI Yaping

Abstract：Objective To study the application value and safety of percutaneous coaxial-core needle biopsy via director assis-ted CT guidance in retroperitoneal lymphomas. Methods From June 2013 to May 2015, a total of 18 patients with retroperitoneal mas-ses couldn't undertaking surgercal biopsy were enrolled in this study. The 18 patients received percutaneous coaxial-core needle biopsy via director assisted CT guidance. At least five biopsy samples from different position were taken for pathology and immunohistochemis-try examination. A dosage of 10-30 mg of cisplatin was injected into the lesion by trocar needle. Results Of the 18 patients underwent percutaneous coaxial-core needle biopsy via director assisted CT guidance. The success rate of puncture and biopsy was 100%. Opera-tion time was 20-40 min (average 30 minutes), and 5-9 sequence with 45-90 pictures of scan were used. No complications such as hemorrhage and pneumothorax occurred. Ten cases of retroperitoneal lymphomas were diagnosed, among whom there were 6 cases of diffuse large B lymphoma, 2 cases of follicular lymphoma and 2 cases of lymphoid cell lymphoma. According to Ann Arbor stage,there were 2 of stage Ⅱ, 6 of stage Ⅲ, and 2 of stage Ⅳ. The combination of chemotherapy and radiation was performed on lymphoma pa-tients. Conclusion Percutaneous coaxial core needle biopsy via director assisted CT guidance with minimal invasiveness and fewer complications is a safe and effective minimally invasive technology, worthy of clinical application in the diagnosis of retroperitoneal lym-phoproliferative disease.