Clinical analysis of 62 cases of cutaneous metastases from internal cancers

WANG Jing; ZHAO Lei; LI Huihui; CHE Juanjuan; PANG Xinqiao; WU Jun; MA Nina

Abstract：Objective To analyze the clinical characteristics of cutaneous metastases from internal cancers, and enhance the understanding of cutaneous metastases. Methods In the retrospective study, the clinical features, primary sites of cancers, morpho-logical features and occurence of 62 cases of cutaneous metastases from internal cancers diagnosed in Beijing Friendship Hospital from January 2002 to December 2015 were analyzed. Results There were 40 males and 22 females among the 62 patients. The median age at the onset of skin lesions was 60. 0 years( range 33-82 years) . Cutaneous metastases occurred at various locations of the body, inclu-ding abdomen, chest, back, scalp, limbs and etc. Abdominal wall was the most common site of cutaneous metastases, accounting for 72. 6% of patients with cutaneous metastases. The most common types of primary cancer were lung cancer, gastric cancer and colorectal cancer. Pathological biopsy showed that 40 cases were in complete agreement with the pathologic types of the primary lesions, and 3 ca-ses were consistent with the morphology of the primary tumors, but the degree of tumor differentiation was different. One case was con-firmed with second primary cancer by skin biopsy. Seventeen patients were comfirmed with cutaneous metastases when the primary cancers were diagnosed. Most patients were diagnosed with cutaneous metastases within 4 years after the primary cancers were com-firmed. Conclusion With increasing incidence of cancers, cutaneous metastases from internal cancers increased in recent years. Rai-sing awareness of cutaneous metastases is helpful for early diagnosis, treatment and prolonging patients’ life.