Research progression of Kruppel-like factor 4 in the digestive system neoplasms
TIAN Chuan
LI Qi
Abstract：Kruppel?like factor 4(Klf4),a zinc finger?type protein transcription factor,plays an important role in the cell growth, apoptosis, proliferation and differentiation by regulating the expression of a number of downstream target genes. Klf4 is a tran?scription factor which functions as a tumor suppressor and oncogene. This article summarizes the structure of Klf4, biological function and latest research progress in digestive system neoplasms.
Keywords：Kruppel-like factor 4Transcription factorFunctionDigestive system neoplasms
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 662-665 )