New discovery of the function research on MDSCs
DENG Wanping
SUN Junzhong
Abstract：Myeloid?derived suppressor cells( MDSCs) is a crowd of cells, which can suppress the immune response, mainly by inhibiting T cells' function, as a result, contributing to the genesis and development of disease. With the increasing importance of MD?SCs as targets for treatment of cancer, more and more people have given considerable attention to it, and have achieved certain results. In this paper we reviewed the MDSCs' immunosuppressive mechanism, and the role of MDSCs as potential targets in animal experi?ments, as well as in clinical researches, aiming at offering new insights into the treatment of malignant tumor.
Keywords：Myeloid-derived suppressor cells( MDSCs)Malignant tumorImmunosuppressiveTherapeutic target
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 474-477 )