Progression of high-mobility group protein A2 in malignant cancer
LIU Yafang
LIU Hongbing
SONG Yong
Abstract：The high mobility group protein A( HMGA) family is composed of four proteins. HMGA2 is one of the family. HM?GA2 involves in epithelial?mesenchymal transition, and plays a crucial role in maintaining the differentiation potential and the self?re?newal of neural stem cells(NSCs).HMGA2 is able to process a number of different mechanisms involved in the regulation of biological events. Overexpression of HMGA2 has been observed in a variety of malignant tumors and often correlates with poor prognosis. In this review, we summarize the latest progresses on HMGA2 in cancer.
Keywords：High-mobility group protein A2( HMGA2)TumormiRNA
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 465-468 )