Comparative analysis of outcomes and incidences of complication in ⅠB-ⅡA cervix cancer with different treatment in Xinjiang

ADALAITI Yasheng; HUERXIDAN Niyazi; ZHANG Song'an; ZHANG Lei; ZHAO Huarong

Abstract：Objective To compare the outcomes and incidences of complication inⅠB?ⅡA cervix cancer with different treat?ment in Xinjiang. Methods In a retrospective study, the clinical and pathological data of 215 patients withⅠB?ⅡA cervical cancer were collected as well as follow?up data. The overall 5?year survival rate was investigated and the stratification analysis of 5?year survival rate was made by clinicopathological parameters. Cox model was used to analyze the independent prognostic factors. According to treat?ment regimens, 215 patients were assigned into 4 groups:radical operation ( n=81) , radical radiotherapy ( n=65) , preoperative adju?vant therapy ( n=25) and postoperative adjuvant therapy ( n=44) . The prognosis and complications were analyzed among 4 groups. Results The overall 5?year survival rate was 79?3%, and varied among different FIGO stages, nations,tumor sizes, degrees of differ?entiation and postoperative risk factor ( P<0?05) . Cox model showed that clinical stage, tumor size, degrees of differentiation and post?operative risk factor were independent prognostic factors for cervical cancer ( P<0?05 ) . The 5?year survival rates were 80?9%, 82?5%, 78?8% and 72?4% and the incidence rates of complication were 25?9%, 18?5%, 24?0% and 38?6% for patients receiving radical operation, radical radiotherapy, preoperative adjuvant therapy or postoperative adjuvant therapy with no significant differences ( P>0?05) . Conclusion For patients with postoperative risk factors and preoperative large tumor volume, the corresponding postoper?ative adjuvant therapy can achieve similar effect as radical operation or radical radiotherapy for patients without risk factors. The indi?vidual treatment was recommended for different patients in the clinical work. In the premise of ensuring the therapeutic effect, every possible effort should be made to reduce complications of patients.