Clinical analysis of cervical cancer with skin metastasis in 5 patients

NA Renhua; ZHANG Yunxia; Gulina Kuerban

Abstract：Objective To explore the clinical features, treatment and prognosis of cervical cancer patients with skin metasta?sis. Methods From June 2006 to June 2011, 574 cervical cancer patients were treated in our hospital, in which 5 cases was diag?nosed as cervical cancer with skin metastasis. The clinical, pathological and follow?up data of 5 patients were collected and their clini?cal features, treatment and prognosis were analyzed. Results The incidence rate of cervical cancer with skin metastasis was 0?? 87%(5/ 574), with stage ⅡA to ⅢB. Among them, 4 cases were diagnosed during the follow?up of cervical cancer. One patient was diag?nosed after resection in her first hospitalization. There were 4 patients with pulmonary, skeletal and other sites of metastasis. Four patients?? skin lesions were excised completely including 1 patient underwent radionuclide therapy because of multiple bone metastases and bone pain, one patient received systemic chemotherapy, 2 patients received only supportive and symptomatic treatment. One patient couldn??t receive complete excision because of metastatic lesions invading skull scalp inward, diagnosed by puncture examination,and underwent conformal intensity modulated radiotherapy. During the follow?up, 3 patients died, 2 patients still alive. Conclusion Cervi?cal cancer with skin metastasis occurs at a low rate, usually combined with other organs?? metastases, and its efficacy and prognosis is poor.